George Panagis Professor in Biopsychology


George Panagis

Professor in Biopsychology

George PanagisGeorge Panagis received his first Bachelor’s Degree from the Department of Philosophy and Social Sciences, University of Crete, Greece (1992), his second Bachelor’s Degree from the Department of Psychology, University of Crete, Greece (1995) and his Ph.D. (1996) from the Medical School, University of Crete, Greece. His doctoral dissertation focused on the role of ventral pallidum in reward.

He was a postdoctoral research fellow (1997-98) in Karolinska Institute (Stockholm, Sweden), where he studied the psychotropic and addictive properties of nicotine in experimental rats. He was appointed as an adjunct faculty member in the Department of Psychology, University of Crete (1995-2000), where he was elected Lecturer in August 2000, Assistant Professor in August 2004, Associate Professor in January 2010 and Professor in June 2015. He has collaboration with the Graduate Program in Neuroscience of the University of Crete. His main interests lie in the following fields:

  • Neural basis of brain stimulation reward.
  • Interactions between drugs of abuse and brain reward systems.
  • The role of endogenous cannabinoid system in behavior and reward.
  • Effects of mood stabilizers on brain reward.
  • Effects of physical exercise on brain reward system and behaviour.

GeorgePanagis has been the author of the book Behavioral Neuroscience: Basic principles, methods, techniques, and laboratory exercises. (Paschalidis Medical Publications, 2002). He has translated and co-edited in Greek the textbooks “Molecules and Mental Illness” (S.Barondes) and “An Introduction to Brain and Behavior” (B. Kolb & I.Q. Whishaw). He has published 48 scientific papers in Greek (8) and international (40) peer-review journals and 4 book chapters and has received more than 1000 citations.

Selected Publications

  1. Panagis G., Hildebrand B.E., Svensson T.H. & Nomikos G.G. (2000) Selective c-fos induction and decreased dopamine release in the the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Synapse, 35, 15-25.
  2. Panagis G., Kastellakis A., Spyraki C. & Nomikos G.G (2000) Effects of methyllycaconitine (MLA), an alpha 7 nicotinic receptor antagonist, on nicotine- and cocaine- induced potentiation of brain stimulation reward, Psychopharmacology, 149, 388-396.
  3. Vlachou, S., Stamatopoulou, F., Nomikos, G.G. and Panagis, G. (2008) Enhancement of endocannabinoid neurotransmission through CB1 cannabinoid receptors counteracts the reinforcing and psychostimulant effects of cocaine, International Journal of Neuropsychopharmacology, 11, 905-923.
  4. Mavrikaki, M., Nomikos, G.G., & Panagis, G. (2009). Effects of Mood Stabilizers on Brain Reward Processes in Rats: Studies Using the Intracranial Self-Stimulation Paradigm, European Neuropsychopharmacology, 19, 205-214.
  5. Mavrikaki, M., Markaki, E., Nomikos, G.G., & Panagis, G. (2010). Chronic WIN55,212-2 elicits sustained and conditioned increases in intracranial self-stimulation thresholds in the rat, Behavioural Brain Research, 209, 114-118.
  6. Katsidoni, V., Apazoglou, K., & Panagis, G. (2011). Role of serotonin 5-HT2A and 5-HT2C receptors on brain stimulation reward and the reward-facilitating effect of cocaine, Psychopharmacology, 213, 337-354.
  7. Katsidoni, V., Anagnostou, I., & Panagis, G. (2013).  Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus, Addiction Biology, 18, 286-296.